After their father passes away, three siblings reconnect at their mother's remarriage.
Robert McCall finds himself at home in Southern Italy but he discovers his friends are under the control of local crime bosses. As events turn deadly, McCall knows what he has to do: become his friends' protector by taking on the mafia.
Finding himself in a new era, and approaching retirement, Indy wrestles with fitting into a world that seems to have outgrown him. But as the tentacles of an all-too-familiar evil return in the form of an old rival, Indy must don his hat and pick up his whip once more to make sure an ancient and powerful artifact doesn't fall into the wrong hands.