When loser Duke, who has screwed up every hair-brained scheme he's ever come up with, accidentally falls off a cruise ship and wakes up on a mysteriously abandoned, top secret government island, he discovers that it's overrun with mutants and monsters from a failed 1980s DARPA "super soldier" project to stop the 2nd Cold War.
When an alcohol-fueled hook up takes a violent and horrifying turn, three college athletes find themselves haunted by the very girl they left for dead.