At the tenth wedding anniversary celebration of Bai Li and her husband, Ye Yun Kai, she meets her college junior, Su Yu. At this time, Su Yu is Ning Mo Chen's boyfriend. Ning Mo Chen schemes to let Bai Li find out that her husband is cheating with her. Later, Bai Li and the mistress fall into the water and their souls are accidentally exchanged. Bai Li wakes up with the mistress' soul and begins her revenge.
Ruan Liuzheng returns to her hometown after seven years, and becomes a neurosurgeon at Beiya Hospital. However, she didn't expect to meet her ex-husband, Ning Zhiqian, who is the most experienced neurosurgeon. Ruan Liuzheng is no longer the weak and timid girl, and she shows resolute and determination in both her work and relationship. When they were in Africa to execute medical relief efforts, Ning Zhiqian was injured in a gunshot. Ruan Liuzheng didn't leave his side, and fought hard to save him from the brink of death. The two have gained a new understanding of life, and begun a new relationship again.
The film tells the story of the snake demon Liqing who charms all living beings. In order to monopolize Wang Sheng, who fell in love at first sight, she enters Wang Sheng's house by any means, and designs to "swap skins" with Wang Sheng's wife Xu Pan. But Liqing did not expect that her actions repeatedly disobeyed her mother-in-law, who collects men's souls, and her selfishness completely angered her, causing Wang Sheng to be in danger again and again. , Can the love between the two continue?
