Dylan, a young man with a beautiful and carefree life, runs, along with his best friend Mike, the "Break-Up Club", a private club that offers assistance to help cope with the breakup. Things are going well until Zoë, a journalist and former employee of the club, starts writing a compromising article about the "Break-Up Club".
Merel, a single midwife, is done with men, but her biological clock is ticking inexorably. And yes, she gets pregnant. However, the whole family suddenly seems pregnant. Her 60-plus father Piet has just become a father again with his young partner and her 23-year-old niece Eva is also expecting. Annet, Merel's older sister, who suffers from the empty nest syndrome, has a husband Theo who only wants to travel because he thinks is too young to become a grandfather.