After a comet releases a mysterious virus that begins to kill all of the women in the world, a young couple's relationship is severely tested. They hide out (from both the illness and the savages who hunt the remaining women) in their over-sterilized apartment. Ultimately the duo escapes their self-imposed quarantine to head to the wilderness.
When a law-abiding woman gets indicted for murdering her husband, her lawyer soon realizes that a larger conspiracy may be at work.