Kate, a conservative widow and single mother builds a nightclub and cocaine empire to support her family, becoming the most dangerous woman in London.
Dr Lucinda Edwards is a smart, battle-hardened doctor, but we meet her on a nightmare shift that ends in the death of an opioid overdose victim, Edith Owusu. Despite the support of her medical supervisor, Dr Leo Harris, Edith’s grieving father Sir Anthony Owusu, demands an enquiry into Lucinda’s actions on the fateful night.