Joel, a caustic 1980s film critic for a national horror magazine, finds himself unwittingly trapped in a self-help group for serial killers. With no other choice, Joel attempts to blend in with his homicidal surroundings or risk becoming the next victim.
When a hotel hallway is ravaged by a dreadful airborne virus, pregnant Japanese runaway wife Naomi is tragically thrust into the fight of her life. After getting infected, she is forced to crawl her way through other helpless victims to escape. In the room next door to her is Val, a mother trapped in a toxic marriage, who must also navigate her way out of the hotel corridor through the long and narrow stretch of isolated carnage, desperately looking for her young daughter Kelly. Will these two women avoid the debilitating sickness and get out alive?