After a missed call and a disturbing voicemail from his former colleague Hella Christensen, investigator Simon Kessler sets off for Nordholm. The commissioner is aware that something bad must have happened. When Hella's sailing boat is recovered at sea, traces of her blood and her cell phone are found on it, but there is no trace of the former commissioner herself. A SOKO, headed by the new police commissioner Lena Jansen, takes over the investigation. The investigative team not only has to solve Hella's disappearance, but also the death of 15-year-old Viviane, who was found in the woods by her friend Charlotte Broder and probably died of a drug overdose. Kessler realizes how little he knew about the life of his former colleague. After years, Hella's sister Rieke Lehwald suddenly appears with her husband Paul. Do the two have something to do with Hella's disappearance? Is it about an inheritance or a relationship act?
When the pictures from Bergamo in Italy go around the world in spring 2020, even non-medical people know what the word pandemic means. The previously unknown Coronavirus is spreading rapidly across the planet. Four days later, exit and contact restrictions also apply in Germany. Since then, the life of the Konstanz intensive care physician Dr. Carolin Mellau and her family on their heads. The female doctor becomes a member of the crisis team and is on duty around the clock to prepare the clinic for the impending emergency. As an anesthesiologist intubating those infected with COVID-19, she herself carries a high risk of infection. Meanwhile, her husband Stefan has to cancel his concerts as a musician, is no longer allowed to teach his music students and is suddenly sitting at home without an income. Teenage daughter Luzy is not allowed to see her Swiss boyfriend because the border is closed. She and brother Tim cannot go to school. But the worst case for the family is yet to come.