When Lady Winsley, the famous American novelist, is discovered dead on the remote Turkish island of Büyükada, the great detective Fergün is sent from Istanbul to solve the murder case. With the help of Azra, the beautiful local hotel tenant, he must confront stubborn members of the island community to untangle well-guarded family secrets and discover who the murderer is.
Ferhat is a hitman working for his criminal uncle. Aslı is a young and idealistic doctor. One day, their roads crossed in the most unexpected way: Aslı is forced to operate on a man that Ferhat had shot.
Eylul the stubborn, school girl turns up to be a strong professional doctor by the help of her teacher Ali Asaf. After years of separation they meet up again but not as a teacher and student, instead as surgeons working side by side. Their love is met by many challenges and the inner conflict of the stubborn women who refuse to yield easily to her heart, refusing to repeat the miserable story of her dead mother.