Jack Gladney, professor of Hitler studies at The-College-on-the-Hill, husband to Babette, and father to four children/stepchildren, is torn asunder by a chemical spill from a rail car that releases an "Airborne Toxic Event" forcing Jack to confront his biggest fear - his own mortality.
JR is a fatherless boy growing up in the glow of a bar where the bartender, his Uncle Charlie, is the sharpest and most colorful of an assortment of quirky and demonstrative father figures. As the boy’s determined mother struggles to provide her son with opportunities denied to her — and leave the dilapidated home of her outrageous if begrudgingly supportive father — JR begins to gamely, if not always gracefully, pursue his romantic and professional dreams, with one foot persistently placed in Uncle Charlie’s bar.
Mary is an ambitious Jamaican woman determined to live a grand life; her adventures take her across oceans and eras, from a battlefield of the Crimean War to a contemporary nursing home, and many times and places in between.