Minato Shindo has savant syndrome. His memory is amazing, but he has difficulty communicating with other people. When Minato was little, he dreamed of becoming a doctor. He met Doctor Akira Shiga and he wanted to become a pediatric surgeon. Akira was surprised by the 7-year-old's memory of the human organs and he decided to support Minato in achieving his dream. Eventually, Minato graduated from medical school and passed the national exam for medical practitioners. Now, Akira works as a director at a large hospital. He suggests to Minato to work in the pediatric surgery department at the hospital where he works.
Higashigaoka High School’s male swimming club presently has only three second-year members – leader Sakaki Shuhei, Shinozuka Daiki and Koganei Haruyoshi. They welcome the new school year with the aim of getting members.
Shiho works as a neurosurgeon at Nishitokyo General Hospital. She decides to quit her profession after hallucinating during surgery. Her ex-teacher Masayuki Kitabatake is the director at Tokyo University Hospital and he persuades Shiho to work at his hospital in the diagnosis department which consists of all female doctors. Shiho, who is more stubborn in her will to save other patients, sometimes come in conflicts with the other doctors there, but she cooperates with them to reveal a mysterious malady.