Fearing he'll never be a success, Barnaby Bates, a struggling LA comedy writer, pulls away from a blossoming romantic relationship with Rose, an empathetic young photographer, in order to focus on his career. Things get complicated when he's visited by a mysterious stranger from the future who warns that the world as Barnaby knows it will soon be coming to an end.
It's 1999 and over the course of one 12-hour shift at an Arkansas hospital, a junkie nurse, her scheming cousin and a group of black market organ-trading criminals start a heist that could lead to their collective demise.