Paris 2020. While superheroes have assimilated into the Parisian society, they discover a new drug that gives themselves personal superpowers to mere mortals. Lieutenants Moreau and Schaltzmann are investigating the case with the support of two ex-superheroes, Monte Carlo and Callista. They'll do whatever it takes to dismantle the traffic. But Moreau's past resurfaces, and the investigation becomes more complicated.
When 43-year-old hairdresser Suze Trappet finds out that she's seriously ill, she decides to go looking for a child she was forced to abandon when she was only 15. On her madcap bureaucratic quest she crosses paths with JB, a 50-year-old man in the middle of a burnout, and Mr. Blin, a blind archivist prone to overenthusiasm. The unlikely trio set off on a hilarious and poignant helterskelter journey across the city in search of Suze's long-lost child.