In the smog-choked dystopian Los Angeles of 2019, blade runner Rick Deckard is called out of retirement to terminate a quartet of replicants who have escaped to Earth seeking their creator for a way to extend their short life spans.
In 2052, a Nobel Prize-winning neuroscientist develops a drug called Hapuna — a cure-all that has the unexpected side-effect of causing death three years later. In response to this threat, a special force of agents—nicknamed "Lazarus"— is assembled to take on the malevolent Skinner.