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A telepathy experiment goes awry and a Quark Scientist, Dr. Neugog, is transformed into a giant brain on spidery legs. Neugog uses his telepathic powers to drain the minds of the world's greatest scientists. Meanwhile, Dr. Slate accidentally discovers that there's a man in the Big Guy suit.
Jonathan David Cook
Big Guy (voice)
Pamela Adlon
Rusty (voice)
Jim Hanks
Dwayne Hunter (voice)
Gabrielle Carteris
Dr. Erika Slate (voice)
Stephen Root
Dr. Donovan (voice)
Kathy Kinney
Jenny (voice)
Kevin Michael Richardson
Garth (voice)
M. Emmet Walsh
Mack (voice)
R. Lee Ermey
General Thornton (voice)